Advanced SystemCare uses a one-click approach to clean, optimize, speed up, and protect your computer.You can also run antivirus software like AVG, Avast, Avria or Kaspersky, etc. The easiest and free way to prevent virus infection is to turn on the real-time protection in Windows Defender and enable Virus & threat protection on your computer.If you can't get into Windows to run a virus scan, you'll need to create a recovery tool that you can use to boot up your computer. How to remove a virus when Windows doesn't work.Scroll through the 'Files to delete' list, and choose Temporary files. Click it and choose Disk Cleanup from the drop-down menu. While you're in Safe Mode, delete your temporary files using the Disk Cleanup tool: Go to the Start menu and scroll down to Windows Administrative Tools.